Prevention is better than cure

نویسندگان

  • A Daunton
  • S Puig
  • P Taniere
  • C Forde
  • D Alderson
  • ON Tucker
چکیده

The vast majority of gastric cancers are sporadic. However, 1-3% arise as a result of inherited gastric cancer predisposition syndromes, generally referred to as hereditary diffuse gastric cancer (HDGC). Of those families that fulfill the clinical criteria for HGDC only 25% have a CDH1 germline mutation. No reliable surveillance technique exists for individuals with HDGC. Difficult decisions have therefore to be made by mutation carriers to proceed with prophylactic total gastrectomy, or undergo lifelong annual surveillance. We present a case of the management of a patient with a documented CDH1 mutation and briefly review the available literature.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Problems and Pitfalls in Crime Prevention

That prevention is better than cure is a rather trite but nevertheless important axiom. It may be tempting, therefore, for those individuals, governments and groups charged with the responsibility of crime prevention to rush into any program that boasts a ’preventative’ approach. This paper is designed to alert those engaged in crime prevention policy-making, planning, implementation and evalua...

متن کامل

Prevention and correction in post-error performance: an ounce of prevention, a pound of cure.

Error detection serves 2 different functions: prevention and cure. Prevention engages post-error slowing to reduce future errors, whereas cure engages processes that correct the error. Thus, prevention predicts post-error slowing, and cure does not. We investigated this distinction in skilled typists in 3 experiments. In Experiment 1, post-error performance was investigated in 800 typists who c...

متن کامل

Prevention Is Better than Cure: The Role of IPO Syndicates in Precluding Information Acquisition

We treat information acquisition by potential investors in initial public offerings as endogenous. With endogenous information, the critical question is why underwriters would allow investors to spend resources acquiring superior information intended solely to effect a wealth transfer. We show that an investment banking syndicate is an institutional arrangement designed to avoid such a transfer...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2012  شماره 

صفحات  -

تاریخ انتشار 2012